Download e-book for kindle: Allogeneic Stem Cell Transplantation (Current Clinical by Mary J. Laughlin, Hillard M. Lazarus

By Mary J. Laughlin, Hillard M. Lazarus

The world over famous physicians and researchers overview either the fundamentals of allogeneic stem mobile transplantation and up to date advances within the box, quite as they relate to antitumor results and graft-versus-host affliction additionally they offer particular decision-tree analyses to steer clinicians in deciding on and handling their allogeneic transplant sufferers. The strategies mentioned hide quite a few parts, starting from stem mobilephone mobilization in general donors, to symptoms for allogeneic transplantation except hematologic malignancies, to using nonmyeloablative conditioning regimens. The authors additionally discover new advancements within the optimum number of unrelated allogeneic grafts (e.g., matched unrelated donor, in part mismatched friend, or umbilical wire blood), the use allogeneic peripheral blood stem telephone vs marrow-derived grafts for transplantation, and the kinetics of immune reconstitution after transplantation.

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64. Champlin R, Khouri I, Kornblau S, et al. Allogeneic hematopoietic transplantation as adoptive immunotherapy. In: Schiller GJ, guest ed. Hematology/Oncology Clinics of North America. B. Saunders, Phialdelphia, 1999, pp. 1041–1057. 65. McSweeney PA, Niederwieser D, Shizuru JA, et al. Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects. Blood 2001;97:3390–3400. 66. Forman SJ, Schmidt GM, Nademanee AP, et al.

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59. Appelbaum FR, Anderson J. Allogeneic bone marrow transplantation for myelodysplastic syndrome: outcomes analysis according to IPSS score. Leukemia 1998;12 (suppl. 1):S25–S29. Chapter 2 / Allogeneic BMT for AML 27 60. Fefer A. Graft-versus-tumor responses. In: Thomas ED, Blume KG, Forman SJ, eds. Hematopoietic Cell Transplantation, 2nd ed. Blackwell Science, London, 1999, pp. 316–326. 61. Fefer A, Sullivan K, Weiden P, et al. Graft versus leukemia effect in man: the relapse rate of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation.

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