By GUPTA V K
Bioactive compounds from ordinary items have attracted the eye of biologists and chemists during the international and are becoming a lot awareness these days for treating a variety of ailments. traditional medications are boon to mankind; they've got fewer unintended effects compared to allopathic drugs. even supposing using ordinary medication is expanding world wide, there are issues concerning the efficacy, protection and scientific review. within the current quantity Efficacy, safeguard & medical Evaluation-Part II of the publication sequence complete Bioactive common items an test has been made to hide significant issues within the box of efficacy, safeguard and scientific overview of bioactive normal items and includes 23 studies and study articles. The publication is written in a lucid variety, and comprises contributions via scientists from quite a few nations around the globe specifically from India, Germany, Australia, Japan, Nigeria, Turkey, U.S.A, Sweden, France and China to cite a number of among them.
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Extra info for Comprehensive Bioactive Natural Products, Volume 3 : Efficacy, Safety & Clinical Evaluation (Part 2)
2007). , 2007). However special approaches for selectivity in chemoprevention and chemotherapy might not be necessary, since garlic and its OSCs exert their anticarcinogenic effects by multiple mechanisms, and since multiple signaling pathways are different/dysfunctional in cancers (Nagini, 2008) leading to a certain selectivity by themselves. In addition, the only reason for selective activity of many clinically used chemotherapeutics is the higher proliferation rate of cancer cells if compared with normal cells.
Z-ajoene induces apoptosis ofHL-60 cells: involvement ofBcl-2 cleavage. Nutr. Cancer, 42: 241-247. G. H. (2007). Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro. J. , 70: 716-721. Y. K (2006). 7 macrophages. J. Agrie. , 54: 3472-3478. W. G. (2004). Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells. Food Chem. , 42: 1543-1552. , Lechner, K and Pirker, R. (1996). Multidrug resistance in leukemias and its reversal.
Inhibition of ICAM-l expression by garlic component, allicin, in gamma-irradiated human vascular endothelial cells via downregulation of the JNK signaling pathway. Int. , 6: 17881795. 32 Compo Bio. Nat. , Vol. , Sureshkumar, A. and Sudhandiran, G. (2008). Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-kappaB, and ERK-2. Mol. Cell. , 311: 157-165. D. v. (2008). Bioactive food components and cancer risk reduction. J. Cell. , 104: 339-356. Sugawara, I.