Download e-book for kindle: Curcumin: Biosynthesis, Medicinal Uses and Health Benefits by Jun Sasaki

By Jun Sasaki

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Extra resources for Curcumin: Biosynthesis, Medicinal Uses and Health Benefits

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Currently, there are no standardized treatments for TD. However antioxidants such as curcumin, may provide an adjuvant to therapy, to prevent the development of antipsychotic drug-induced TD. Experimental Evidence for Curcumin in Animal Models The most widely accepted animal model of human TD is the rat vacuous chewing movement (VCM)(Turrone et al. 2002). Rats treated chronically with Haloperidol have been demonstrated to display increased VCMs, tongue protrusions and facial jerking (Bishnoi et al.

And Kulkarni, S. K. (2011) Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence. Neurotox Res. 20: 215-225. Bondy, M. , Scheurer, M. , Barnholtz-Sloan, J. , Davis, F. , McCarthy, B. , Schwartzbaum, J. , Wiemels, J. , and Buffler, P. A. (2008) Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer 113: 1953-1968. , West, A. , Datta, S. , Takasu, M.

Toxicol 89: 217-224. Ghoneim, A. , Abdel-Naim, A. , Khalifa, A. , and El Denshary, E. S. (2002) Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain. Pharmacol. Res. 46: 273-279. , and Offen, D. (2001) Oxidative stress inducedneurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacology 40: 959-975. Giri, R. , and Kalra, V. K. (2004) Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor.

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