By Rita Conigliaro, Marzio Frazzoni
In this e-book, major foreign specialists describe and speak about many of the ideas to be had for the screening, prognosis, administration, and follow-up of digestive illnesses, supplying clinically worthy, up to date studies that draw upon their very own event and concentration cognizance at the latest advances within the box. one of the wide selection of themes coated are using confocal laser endomicroscopy within the gastrointestinal tract, endoscopic suture platforms, endoscopic submucosal dissection, in step with oral endoscopic myotomy, and cholangioscopy structures. The event of a number one surgical crew within the software of endoscopic radiofrequency ablation in pancreatic melanoma is pronounced, and new surgical and endoscopic options for the remedy of Zenker's diverticulum are proposed. The remaining chapters research the current and way forward for esophageal motility checking out and the diagnostic yield of novel parameters in reflux tracking. as well as the dialogue of strategies, suggestion is supplied on education, endoscopy and imaging gear, and set-up of endoscopy devices in the course of procedures.
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Specific mutations in the PALB2 gene have recently been identified as possibly increasing susceptibility for pancreatic cancer . In 70 % of cases, the tumor is located in the pancreatic head, and symptoms are usually related to the involvement of surrounding structures: the duodenum and common bile duct. For tumors of the body and tail, the diagnosis can be late due to nonspecific symptoms (back pain, abdominal discomfort, dyspepsia), particularly when the disease is advanced and the mass has enough room to expand.
The posterior duodenum); although heater probe is an effective alternative method to treat such lesions, this treatment modality is available in the USA and some Asian countries only but not in most European countries. However, using a heater probe can result in a higher risk of perforation . The authors also claimed that the placement of OTSC was easy . A more recent study reported a series of patients in whom OTSC represented the first-line endoscopic treatment in patients with high-risk nonvariceal upper gastrointestinal bleeding .
47] Baron et al.  Disibeyaz et al.  Galizia et al.  Menningen et al.  Haito-Chavez et al.  Winder et al.  Farnick et al. S. S. S. S. S. S. R. 4) [54, 63, 64, 70, 71, 81–91]. Difficulties arise in the treatment of chronic leaks. The failure of this technique is more frequent when the leak edges are fibrotic and in patients who had undergone several surgical approaches. Indeed, Albert et al. found that success was high and durable when the time from diagnosis to application of the clip was within 1 week, resulting in a success rate of 100 % in postoperative lesions .