Read e-book online Discovery of Novel Natural Products with Therapeutic PDF

By Author Unknown, Vincent P. Gullo

Even if technology has came across potent medications for plenty of of the illnesses that afflict mankind, many human illnesses stay untreatable. the hunt for novel healing brokers is usually ongoing. This e-book will describe the various varied sources
of common items, equivalent to terrestrial and marine environments; and may evaluation how study has elevated wisdom of organic platforms and human sickness, resulting in the layout of designated asssays, amenable to excessive quantity screening.

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1962) Phytopathology 52, 317-323. M. (1971) Trans. Y. Acad. Sei. 33, 207-218. M. (1991) Actinomycetes 2(Suppl. 1), 1-149. , et al. (1983)7. Antibiot. 36, 1101-1108. , Truumees, L, et al. (1976a) 172nd Annual Meeting of the American Chemical Society, Abstract no. MICR 55, New Orleans, LA. J. (1976b) /. Antibiot. 29, 483-487. , and Broda, P. (1984) /. Gen. Microbiol. 130, 2905-2913. , and Ohara, Y (1969) /. Ferment. Technol. 47, 463-469. , and Okami, Y. ), pp. 123-161, Toppan Co. Limited, Tokyo.

II, 2nd ed. ), pp. 10611068, Springer-Verlag, New York. C. ), pp. 1-19, McGraw-Hill, New York. P. (1981) in The Procaryotes, A Handbook on Habitats, Isolation, and Identification of Bacteria, vol. II, 1st ed. ), pp. 1915-1922, Springer-Verlag, New York. A. ), pp. 315-358, Benjamin/ Cummins, Menlo Park, CA. L. (1962) Phytopathology 52, 317-323. M. (1971) Trans. Y. Acad. Sei. 33, 207-218. M. (1991) Actinomycetes 2(Suppl. 1), 1-149. , et al. (1983)7. Antibiot. 36, 1101-1108. , Truumees, L, et al. (1976a) 172nd Annual Meeting of the American Chemical Society, Abstract no.

When the culture is believed pure, one may streak this onto a richer media that is capable of supporting growth of a wider range of potential contaminants, in order to verify that it is axenic. 5 PRESERVATION AND MAINTENANCE Maintaining growth of cells does not necessarily mean maintaining productivity of cells, thus one must consider both qualities carefully when determining how to preserve the culture. , the ability to produce the metabolite of interest. There is no excuse for trying to maintain bacterial cultures by continuous subculture or by freezing at - 20°C.

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