Download e-book for kindle: Gastrointestinal Pathology, An Issue of Gastroenterology by Robert D. Odze MD FRCP(C)

By Robert D. Odze MD FRCP(C)

As a result of fresh advances in endoscopy and radiology, there's elevated attractiveness of the superiority and organic features of neoplastic precursor lesions within the GI tract, liver, biliary tract, and pancreas. consequently, there were significant fresh advancements within the pathologic category, analysis, molecular pathogenesis, traditional background and therapy of those lesions. additionally, there are debatable concerns in regards to the price of endoscopic screening and surveillance. a detailed clinician-pathologist interplay is key within the administration of preneoplastic lesions. during this factor the pathology, organic houses, pathogenesis, average background, and present therapy techniques of the key preneoplastic and dysplastic precursor lesions of the GI tract, liver, biliary tract and pancreas are reviewed intimately. anywhere attainable, accessory is given to debatable diagnostic and management-related matters. every one material is written via specialists within the box, all of whom have had study adventure of their respective parts.

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HPV DNA has been isolated from esophageal squamous carcinomas at prevalence rates that vary from 0% to 66% [30–33]. Some have reported that HPV infection is not a major risk factor for esophageal squamous cell carcinoma in high-risk populations, such as China, whereas others suggest that the presence of either HPV-16 or -18 may be causally related to cancer development [34,35]. Varying rates of HPV positivity between different studies may be related to differences in techniques used to detect HPV, and to differences in patient populations.

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810 SHIMIZU, BAN, & ODZE [26] Munoz N, Crespi M, Grassi A, et al. Precursor lesions of oesophageal cancer in high-risk populations in Iran and China. Lancet 1982;1(8277):876–9. [27] Guanrei Y, Songliang Q. Endoscopic surveys in high-risk and low-risk populations for esophageal cancer in China with special reference to precursors of esophageal cancer. Endoscopy 1987;19(3):91–5. [28] Qiu SL, Yang GR. Precursor lesions of esophageal cancer in high-risk populations in Henan Province, China. Cancer 1988;62(3):551–7.

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