By Joseph I. Boullata, Vincent T. Armenti
This instruction manual presents a vital compilation of present info on drug-nutrient interactions that may permit wellbeing and fitness care companies to raised deal with their sufferers. It bargains evidence-based scientific strategies for plenty of interactions, and serves as an important instrument for clinicians to exploit in figuring out, making a choice on, distinguishing, predicting, optimizing, handling and fighting major opposed drug-nutrient interactions with a view to optimize sufferer care.
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Additional resources for Handbook of Drug-nutrient Interactions
J Pharmacol Exp Ther 1977;201:527– 533. Peterson FJ, Holloway DE, Duquette PH, et al. Dietary ascorbic acid and hepatic mixed function oxidase activity in the guinea pig. Biochem Pharmacol 1983;32:91–96. Zannoni VG, Flynn EJ, Lynch MM. Ascorbic acid and drug metabolism. Biochem Pharmacol 1972;21:1377–1392. Sato PH, Zannoni VG. Stimulation of drug metabolism by ascorbic acid in weanling guinea pigs. Biochem Pharmacol 1974;23:3121–3128. Beattie AD, Sherlock S. Ascorbic acid deficiency in liver disease.
Variability from genetic, gender, and age factors would also need to be taken into account. Similarly, any change in nutritional status should be evaluated for drug-related causes. It would be difficult to study high-risk populations such as the elderly and those with chronic conditions because of issues of consent or the time lapse involved in appreciating nutritional deficiencies. A further constraint is the limited funding available for nutritionrelated research, particularly in this subject matter.
9. Hathcock JN, Coon J. (eds). Nutrition and Drug Interrelations. Academic Press, New York, NY, 1978. 10. Roe DA, March DC. ). American Dietetic Association, Chicago, IL, 1982. 11. Lerman F, Weinbert R. Drug Interactions Index. Medical Economics, Montvale, NJ, 1982. 12. Winick M. ). Nutrition and Drugs. Wiley, New York, NY, 1983. 13. Roe DA, Campbell TC. Drugs and Nutrients: the Interactive Effects. Marcel Dekker, New York, NY, 1984. 14. Roe DA. ). AVI Publishing, Westport, CT, 1985. 15. Schwartz J, Williams R, Savage J.