By Warkentin Theodore, Andreas Greinacher
Up-to-date and revised, this paintings explores the pathogenesis, medical presentation, analysis, and remedy of blood clots brought on by anticoagulants. It offers 10 medical ideas for spotting and treating heparin-induced thrombocytopenia (HIT).
Read or Download Heparin-Induced Thrombocytopenia, 2nd Edition (Fundamental and Clinical Cardiology) PDF
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Additional info for Heparin-Induced Thrombocytopenia, 2nd Edition (Fundamental and Clinical Cardiology)
Towne JB, Bernhard VM, Hussey C, Garancis JC. White clot syndrome. Peripheral vascular complications of heparin therapy. Arch Surg 114:372–377, 1979. Trowbridge AA, Caraveo J, Green JB III, Amaral B, Stone MJ. Heparin-related immune thrombocytopenia. Studies of antibody–heparin specificity. Am J Med 65:277–283, 1978. Wahl TO, Lipschitz DA, Stechschulte DJ. Thrombocytopenia associated with antiheparin antibody. JAMA 240:2560–2562, 1978. Wallis DE, Workman DL, Lewis BE, Steen L, Pifarre R, Moran JF.
A 14-year study of heparin-induced thrombocytopenia. Am J Med 101:502–507, 1996. Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, Kelton JG. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 332:1330–1335, 1995. Warkentin TE, Elavathil LJ, Hayward CPM, Johnston MA, Russett JI, Kelton JG. The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Ann Intern Med 127:804–812, 1997.
Onyalai An exceptionally severe variant of AITP, onyalai, is observed in some black populations in southern Africa. Whites living in the same regions do not appear to suffer from this disease. In a series of 103 patients (Hesseling, 1987), all patients presented with hemorrhagic bullae of the mucous membranes of the oropharynx. Six died, four of cerebral hemorrhage and two of hemorrhagic shock. Clinical diagnosis is based on the critera of AITP and, in addition, to the presence of hemorrhagic bullae (Hesseling, 1992).