By J.C. Osselaer
Complement factor: Transfusion medication and Hemotherapy 2004, Vol. 31, Suppl. 1
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Additional resources for Meeting the Challenges of Blood Safety in the 21st Century: Pathogen Inactivation
43 Davey RJ, McCoy NC, Yu M, et al: The effect of prestorage irradiation on post-transfusion red cell survival. Transfusion 1992;32: 525–528. 44 Moroff G, George VM, Siegl M, et al: The influence of irradiation on stored platelets. Transfusion 1986;26:453–456. 45 Read EJ, Kodis C, Carter CS, et al: Viability of platelets following storage in the irradiated state. A pair-controlled study. Transfusion 1988;28:446–450. 46 Sweeney JD, Holme S, Moroff G: Storage of apheresis platelets after gamma irradiation.
Transfusion 1993;33:447–449. 35 Linden JV, Pisciotto PT: Transfusion-associated graft-versus-host disease and blood irradiation. Transfus Med Rev 1992;6:116–123. 36 Shlomchik WD, Couzens MS, Tang CB, et al: Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 1999;285:412–415. 37 Gresens CJ, Paglieroni T, Moss CB, et al: Tcells in fresh frozen plasma are viable and can respond to mitogen, superantigen and allogeneic monocytes (abstract). Transfusion 1999;39:99S.
30 * Optimum swirling is 3 (graded 0–3). Implementing INTERCEPT for Buffy Coat Platelets in a Blood Center Transfus Med Hemother 2004;31(suppl 1):32–36 33 3 on the day of production. 9 (range 2–3). % Plasma 50 40 30 20 10 Logistics A B C 0 Plasma ratio Plasma ratio — minimum Plasma ratio — maximum Fig. 3. Plasma content in BC concentrates. Region A represents data before standardization started, region B is the standardization period and region C is the validation period. gation cycle was 4,260 g (maximum) for 10 min, and the secondary centrifugation cycle was 800 g (maximum) for 4 min.