By Syed A. Abutalib, Jean M. Connors, Margaret V. Ragni
This ebook, in Q&A structure, addresses quite a lot of clinically proper issues and concerns in Nonmalignant Hematology, or “Benign Hematology,” with the intention to delivering a powerful, enticing device that would help each hematologist and oncologist (pediatric and grownup both) in making judgements in the course of daily perform. the whole spectrum of the uniqueness is roofed in additional than 60 extraordinary chapters written via said specialists within the box. The content material is equipped into well-designed large sections on pink mobile issues, platelet and coagulation problems, coagulopathy in systemic illnesses, thromboembolic illness and its administration (including surgical), immune process and comparable problems, hemostasis and thrombosis while pregnant and within the infant and aged, and Transfusion drugs. A key point of the ebook is the chance it gives professional physicians to precise well-reasoned critiques relating to advanced matters in Nonmalignant Hematology. Readers will locate that it presents a pragmatic and instantly acceptable compendium of solutions to occasionally complicated and vexing questions. it's going to attract citizens, fellows, residence officials and more matured practitioners round the globe.
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Extra info for Nonmalignant Hematology: Expert Clinical Review: Questions and Answers
2012;65(11):976–80. Tishler PV. Treatment of erythropoietic protoporphyria with the oral sorbent colestipol: a proof-of-concept clinical trial. J Am Acad Dermatol. 2014;70(2):391–2. Disorders of Hemoglobin Synthesis: Pathophysiology and Diagnostic Evaluation Elena Cassinerio, Giovanna Graziadei, and Maria Domenica Cappellini Introduction Hemoglobinopathies are the most common inherited red cell disorders worldwide among which thalassemias and sickle cell syndromes constitute the two main groups.
Cau M, Galanello R, et al. Responsiveness to oral iron and ascorbic acid in a patient with IRIDA. Blood Cells Mol Dis. 2012;48(2):121–3. Chambers JC, Zhang W, et al. Genome-wide association study identiﬁes variants in TMPRSS6 associated with hemoglobin levels. Nat Genet. 2009;41(11):1170–2. Chen WC, Chen YH, et al. Gastrointestinal hemorrhage in warfarin anticoagulated patients: incidence, risk factor, management, and outcome. Biomed Res Int. 2014;2014:463767. Collins JF, Anderson GJ. Chapter 71: Molecular mechanisms of intestinal iron transport.
The effects of hypoxia and inﬂammatory cytokines are better deﬁned. Hepcidin secreted by hepatocytes into the circulation travels to enterocytes, macrophages, and other cell types to determine how much iron they release into the plasma (From: Collins and Anderson 2012, with permission) Which of the following statements about gastrointestinal (GI) blood loss and evaluation of the etiology is correct? D. Blood loss from the GI tract is the only cause of iron deﬁciency anemia in men. A. The patient should have endoscopic evaluation of the GI tract to identify a possible source of bleeding.